Neue MS-Medikamente
Vitamin D
Wird in der Haut unter Einwirkung von UV-Licht aus seinen Vorstufen gebildet. Hohe Vitamin D-Spiegel sollen das Risiko
vermindern, an MS zu erkranken, ob es auch die Krankheitsaktivität einer bestehenden MS vermindern kann, wird kontrovers
diskutiert. Ein Fläschen Oleovit D
3
kostet in der Apotheke übrigens weniger als 3 Euro.
Anm. des Autors dieser Homepage: Ich führe tgl. 10 - 20 Tropfen Oleovit D
3
zu und kontrolliere vierteljählich meinen Vit. D-Spiegel.
Besprechen Sie Ihr Vorgehen mit Ihrem Arzt.
Vit D auf den Haaransatz getropft soll übrigens das Haarwachstum fördern - http://www.zentrum-der-gesundheit.de/duennes-
haar.html.
5. 1. 2010 (aktualisiert); amsel.de; Vitamin D und MS-Symptome? Das flüchtige Prohormon reduziert möglicherweise die
Schubrate deutlich, so australische Forscher. Ein schottisches Team sieht ein erhöhtes MS-Risiko bei Aprilgeborenen.
http://www.amsel.de/multiple-sklerose-news/medizin/index.php?kategorie=medizin&anr=3451
„Nun hat eine Studie mit rund 150 Personen in Tasmanien (einer Insel südöstliche von Australien) ergeben, dass der Vitamin-D-
Spiegel und MS-Symptome in Zusammenhang stehen könnten.“
12. 1. 2010; Leben mit MS; Vitamin D könnte MS-Symptome lindern;
http://www.leben-mit-ms.de/news/aktuell/vitamin-d-koennte-ms-symptome-lindern/246534/1/
11. 2. 2010; pressetext.at; Sonnenbaden macht Männer scharf, Vitamin-D hebt Testosteronspiegel deutlich
an;http://www.pressetext.at/news/100211026/sonnenbaden-macht-maenner-scharf/
9. 4. 2010; DWSG; Vitamin D und Multiple Sklerose: Gibt es einen Zusammenhang?
http://www.dmsg.de/multiple-sklerose-news/index.php?w3pid=news&kategorie=forschung&anr=2129
28. 4. 2010; Neurology; A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis
http://www.neurology.org/cgi/content/abstract/74/23/1852
„Conclusions: High-dose vitamin D (10,000 IU/day) in multiple
sclerosis is safe, with evidence of immunomodulatory effects.“
Jun. 2010; PubMed.gov; Vitamin D and multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/20494325
20. 5. 2010; Aktiv mit MS; UV-Licht oder Vitamin D – was lindert die Symptome der Multiplen Sklerose?
http://www.aktiv-mit-ms.de/0-219-news.html
June 2010; The Lancet Neurology, Volume 9, Issue 6, Pages 599 – 612; Vitamin D and multiple sclerosis
http://www.thelancet.com/journals/lancet/article/PIIS1474-4422(10)70086-7/abstract
1. 6. 2010; amsel.de; Sonnenbad statt Vitamin D?
http://www.amsel.de/multiple-sklerose-news/index.php?kategorie=medizin&cnr=32&anr=3647
29. 6. 2010; aerzteblatt.de; Vitamin D beeinflusst die geistige Aktivität
http://www.aerzteblatt.de/nachrichten/41781/Vitamin_D_beeinflusst_die_geistige_Aktivitaet.htm
29. 6. 2010; Leben mit MS; Vitamin D beeinflusst die Schubrate bei Kindern mit Multipler Sklerose
http://www.leben-mit-ms.de/news/aktuell/vitamin-d-beeinflusst-die-schubrate-bei-kindern-mit-multipler-sklerose/252311/1/
8. 6. 2010; Aktiv mit MS; Sonnenscheue Mütter könnten das Multiple-Sklerose-Risiko ihrer Babys erhöhen
http://www.aktiv-mit-ms.de/0-222-news.html
6. 7. 2010; AerzteZeitung.de; Mehr Sonne, seltener MS?
http://www.aerztezeitung.de/medizin/krankheiten/neuro-psychiatrische_krankheiten/multiple_sklerose/default.aspx?sid=610501
30. 9. 2010; Leben mit MS; Neue Hinweise auf die Bedeutung von Vitamin D
http://www.leben-mit-ms.de/news/aktuell/neue-hinweise-auf-die-bedeutung-von-vitamin-d/254849/
19. 10. 2010; Leben mit MS; Vitamin D könnte vor Krankheitsschüben schützen
http://www.leben-mit-ms.de/news/aktuell/vitamin-d-koennte-vor-krankheitsschueben-schuetzen/255793/
2. 11. 2010; PubMed.gov; The emerging role of vitamin D binding protein in multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21042807
„Several recent studies show that DBP (Vitamin D binding protein) levels in the cerebrospinal fluid correlate with MS course, being
lower during relapses and higher in the secondary progressive phase. Further studies are needed to elucidate the potential use of
DBP as a biological marker of MS course, but may be of use given the current lack of diagnostic tools for the prediction of MS
development and progression.“
3. 11. 2010; PubMed.gov; Vitamin D metabolites are associated with clinical and MRI outcomes in multiple sclerosis
patients.
http://www.ncbi.nlm.nih.gov/pubmed/21047880
„Conclusions Vitamin D metabolites have protective associations with disability and brain atrophy in MS. In particular, the results
indicate strong associations for the 24, 25(OH)(2)VD(3) metabolite, which has not been extensively investigated in MS patients.“
3. 11 2010; Leben mit MS; Wissenschaftler setzt sich für umfassende Untersuchungen zu Vitamin D ein
http://www.leben-mit-ms.de/news/aktuell/wissenschaftler-setzt-sich-fuer-umfassende-untersuchungen-zu-vitamin-d-ein/255804/
10. 11. 2010; amsel.de; Raus mit uns an die frische Luft!
http://www.amsel.de/multiple-sklerose-news/medizin/index.php?kategorie=medizin&anr=3792
26. 11. 2010; Leben mit MS; Vitamin D-Schutzeffekt bei Frauen stärker ausgeprägt als bei Männern
http://www.leben-mit-ms.de/news/aktuell/vitamin-d-schutzeffekt-bei-frauen-staerker-ausgepraegt-als-bei-maennern/255822/
1. 12. 2010; aerzteblatt.de; USA: Vitamin D- und Kalzium-Supplemente meist unnötig
http://www.aerzteblatt.de/nachrichten/43722/USA_Vitamin_D-_und_Kalzium-Supplemente_meist_unnoetig.htm
1. 12. 12010; e-med forum; Klinik und MRT-Befunde der MS hängen mit Vitamin-D-Metaboliten zusammen
http://www.emed-ms.de/index.php?id=533&tt_news=1517
8. 12. 2010; PubMed.gov; Vitamin D for the management of multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21154396
„The trial provided some evidence of the potential benefit of the intervention on several outcomes i.e. the annualised relapse rate;
EDSS scores; suppression of T-cell proliferation and illustrated a measure of comparative safety in the relative absence of any
adverse events or of high serum calcium levels over the study period.“
13. 12. 3010; PubMed.gov; Safety and T Cell Modulating Effects of High Dose Vitamin D(3) Supplementation in Multiple
Sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21179201
16. 12. 2010; PubMed.gov; Sun Exposure, Vitamin D and Age at Disease Onset in Relapsing Multiple Sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21160231
„Conclusions: The current study provides evidence for an association between vitamin-D-related exposures during childhood and
early adolescence and the timing of MS symptom onset, and supports vitamin D as a potential modulator of the clinical course of
this disease.
6. 1. 2011; PubMed.gov; Vitamin D status and antibody levels to common viruses in pediatric-onset multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21212086
„Conclusions: Vitamin D status may be differentially associated with antibody levels to common childhood viruses among
seropositive subjects.“
10. 1. 2011; Pressemitteilungen-online.de; Vitamin D-Mangel - 15 Minuten in der Mittagssonne empfohlen
http://www.pressemitteilungen-online.de/index.php/vitamin-d-mangel-15-minuten-in-der-mittagssonne-empfohlen/
Feb. 2011; PubMed.gov; Vitamin D metabolites are associated with clinical and MRI outcomes in multiple sclerosis
patients.
http://www.ncbi.nlm.nih.gov/pubmed/21047880
Apr. 2011; PubMed.gov; Vitamin D has a direct immunomodulatory effect on CD8+ T cells of patients with early multiple
sclerosis and healthy control subjects.
http://www.ncbi.nlm.nih.gov/pubmed/21186064
18. 6. 2011; Neurology; Lower serum vitamin D levels are associated with a higher relapse risk in multiple sclerosis
http://www.neurology.org/content/79/3/261.abstract?sid=de415849-1503-4e1d-b0c9-a0521f5d8747
„Conclusions: Our finding that higher vitamin D levels are associated with decreased exacerbation risk in relapsing-remitting MS
suggests a beneficial effect of vitamin D on disease course in MS. However, the possibility of reverse causality cannot be ruled out
completely. Randomized intervention studies are therefore needed to investigate the effect of vitamin D supplementation in MS.“
10. 11. 2010; MS-Gateway; Klinik und MRT-Befunde der MS hängen mit Vitamin-D-Metaboliten zusammen
www.ms-gateway.de/scripts/pages/1366.php
1. 9. 2011; PubMed.gov; Vitamin D in the elderly: 5 points to remember.
http://www.ncbi.nlm.nih.gov/pubmed/21896429
„A daily intake of at least 800-1,000 IU supplemental vitamin D(3) per day is the key.“
19. 9. 2011; e-med forum: Gene, Entzündungen und die Rolle des Vitamin D bei MS
http://www.emed-ms.de/index.php?id=533&tt_news=1704http://www.emed
10. 10. 2011; PubMed.gov; Lack of association between vitamin D levels and bone mineral density in patients with multiple
sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/21992813
„CONCLUSIONS: We documented no correlation between vitamin D levels and decreased BMD (bone mineral density) at femoral
neck and lumbar spine in RRMS (relapsing-remitting MS) patients. Vitamin D insufficiency appears not to be the underlying cause
of secondary osteoporosis in MS.“
19. 10. 2011; Leben mit MS; So schützt Vitamin D vor MS
http://www.leben-mit-ms.de/de/patientenundangehoerige/nachrichten/archiv/so_schuetzt_vitamin_d_vor_ms-
006838406.html?mode=detail&newsid=1319006838406&vcid=006838406&backUrl=patientenundangehoerige/nachrichten/archiv/
nachrichten-812.html?mode=archiv+9
25. 10. 2011; Neurology; A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis
http://www.neurology.org/content/77/17/1611.abstract?sid=ac04379c-792a-449f-bd64-8d2d6733fe8f
„Conclusion: We did not find a therapeutic advantage in RRMS for high-dose D2 over low-dose D2 supplementation.“
30. 1. 2012; amsel.de; Wirkung einer Vitamin D-Gabe nur bei bestimmten Personengruppen und Patienten gesichert
http://www.emed-ms.de/index.php?id=533&tt_news=1789
21. 2. 2011: PubMed.gov; Effect of vitamin D3 supplementation on relapses, disease progression and measures of
function in persons with multiple sclerosis: exploratory outcomes from a double-blind randomised controlled trial.
http://www.ncbi.nlm.nih.gov/pubmed/22354743
"Conclusion: Supplementation with 20,000 IU vitamin D(3) weekly did not result in beneficial effects on the measured multiple
sclerosis-related outcomes. This study was not powered to address clinical outcomes, but none of the results were suggestive of
an effect in this unselected population of fully ambulatory persons with multiple sclerosis."
6. 3. 2012; Aktiv mit MS; Bewusster Umgang mit Vitamin D bei Multipler Sklerose gefordert
http://www.aktiv-mit-ms.de/aktiv-leben/ms-ticker/ms-meldungen/ernaehrung-und-ms-bewusster-umgang-mit-vitamin-d-bei-
multipler-sklerose-gefordert-1/
10. 4. 2012; PubMed.gov; Vitamin D for prevention of diseases?
http://www.ncbi.nlm.nih.gov/pubmed/22492477
" Even a controlled supplementation of vitamin D in patients with vitamin D deficiency is considered as reasonable. However, an
uncritical substitution of high-dose vitamin D should be avoided because of the risk of hypercalcaemia."
6. 8. 2012; Aktiv mit MS; Hoher Vitamin D-Spiegel reduziert MS-Risiko bei klinisch isoliertem Syndrom
http://www.aktiv-mit-ms.de/aktiv-leben/ms-ticker/ms-meldungen/kongressbericht-hoher-vitamin-d-spiegel-reduziert-ms-risiko-bei-
klinisch-isoliertem-syndrom/
23. 8. 2012; MSJ; Effect of vitamin D
3
supplementation on relapses, disease progression, and measures of function in
persons with multiple sclerosis: exploratory outcomes from a double-blind randomised controlled trial
http://msj.sagepub.com/content/18/8/1144.abstract
„Conclusion: Supplementation with 20,000 IU vitamin D
3
weekly did not result in beneficial effects on the measured multiple
sclerosis-related outcomes. This study was not powered to address clinical outcomes, but none of the results were suggestive of
an effect in this unselected population of fully ambulatory persons with multiple sclerosis.“
Aug. 2012; PubMed.gov; Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/22926855
„INTERPRETATION: Vitamin D levels are inversely associated with MS activity on brain MRI. These results provide further support
for a randomized trial of vitamin D supplementation. ANN NEUROL 2012;72:234-240.“
30. 8. 2012; Leben mit MS; Hoher Vitamin-D-Spiegel reduziert das Risiko für das Entstehen einer Multiplen Sklerose
http://www.leben-mit-ms.de/de/patientenundangehoerige/nachrichten/hoher_vitamin-d-
spiegel_reduziert_das_risiko_f%C3%BCr_das_entstehen_einer_multiplen_sklerose-
310484965.html?mode=detail&newsid=1346310484965&vcid=310484965&backUrl=patientenundangehoerige/nachrichten/nachric
hten-216.html
6. 11. 2012; aerzteblatt.de; Länger leben mit weniger Vitamin D?
http://www.aerzteblatt.de/blog/52302
27. 11. 2012; PunMed.gov; Role of Vitamin D in the Onset, Progression and Severity of Multiple Sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/23186958
„Conclusion: Vitamin D deficiency in MS patients should be avoided. In addition, the risk of developing MS might be reduced by
maintaining optimal vitamin D levels in the healthy population. Larger randomized interventional trials are needed to clarify the
therapeutic effect of vitamin D in MS.“
14. 12. 2012; PubMed.gov; Vitamin D in Systemic and Organ-Specific Autoimmune Diseases.
http://www.ncbi.nlm.nih.gov/pubmed/23238772
„In addition, we discuss the correlations between vitamin D levels and clinical manifestations and/or activity of diseases. In this
context, we address the rational for vitamin D supplementation in patients suffering from autoimmune diseases.“
(Anm. des Autors dieser Homepage: Z.b. mit OLEOVIT D
3
-Tropfen, die kosten in der Apotheke etwa 2 €. Besprechen Sie es mit
ihrem Arzt.)
27. 12. 2012; Ärzte Zeitung; Weniger Infekte mit Vitamin D
http://www.aerztezeitung.de/medizin/krankheiten/infektionskrankheiten/erkaeltungskrankheiten/default.aspx?sid=829063&cm_mm
c=Newsletter-_-Newsletter-C-_-20121227-_-Erk%C3%A4ltungs-Krankheiten
2012; PubMed.gov; Vitamin D supplementation and monitoring in multiple sclerosis: who, when and wherefore.
http://www.ncbi.nlm.nih.gov/pubmed/23278659
„CONCLUSION: We recommend that MS patients are supplemented with 800 IU of vitamin D at least from autumn to spring.
Alternatively, 25-hydroxyvitamin D should be measured and the nadir level estimated and supplementation given to a target level
between approximately 75 and 125 nm.“
Nov. 2000; PubMed.gov; Vitamin D: a natural inhibitor of multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/11115787
2011; PubMed.gov; Therapeutic effect of vitamin D3 in multiple sclerosis patients.
http://www.ncbi.nlm.nih.gov/pubmed/21542721
„Our results showed no significant difference between the treatment and the control groups in the expanded disability status scale
scores and number of gadolinium-enhancing lesions during the 6-month treatment period. After 6 months, the levels of cell
proliferation in the vitamin D treatment group were significantly lower than the control group. Also, the levels of transforming growth
factor-beta and interleukin-10 in the vitamin D treatment group were significantly higher than the control group. This result
suggests that vitamin D therapy may help prevent the development of MS and could be a useful addition to the therapy.“
22. 1. 2013; PubMed.gov; Vitamin D-binding Protein in Cerebrospinal Fluid is Associated with Multiple Sclerosis
Progression.
http://www.ncbi.nlm.nih.gov/pubmed/23339019
„In conclusion, here we observed upregulated DBP (Vitamin D-binding protein) in the cerebrospinal fluid could serve as a specific
diagnostic biomarker for the progression of multiple sclerosis. Next, we demonstrate the vital function of increased levels of free
vitamin D metabolites for multiple sclerosis treatment. Finally, vitamin D supplements may be particularly beneficial for SPMS
patients.“
Feb. 2013; PubMed.gov; [Vitamin D and multiple sclerosis].
http://www.ncbi.nlm.nih.gov/pubmed/23400652
„CONCLUSIONS. Observation-based studies have shown a consistent inverse relationship between concentrations of vitamin D
and the risk of MS. The intervention studies (basically randomised double-blind placebo-controlled trials), however, offer data that
are not conclusive. The current context opens up the possibility of conducting prospective and intervention-based studies in the
future that will settle the nature of this association in a more convincing manner.“
19. 2. 2013; PubMed.gov; Vitamin D as a clinical biomarker in multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/23480560
„Expert opinion: Mounting evidence from epidemiology, genetic, retrospective clinical studies and emerging basic science studies
support a strong rationale for how vitamin D could be an important modifier of MS disease. Well-designed clinical trials are now
ongoing and will provide further insight on how vitamin D supplementation may impact MS.“
Mar. 2013; PubMed.gov; Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/23483715
„While awaiting these incontrovertible results, which might be long in coming, patients with MS who are currently in vitamin D
insufficiency should be supplemented, at least for their general health status, using moderate doses of the vitamin.“
22. 5. 2013; PubMed.gov; The effect of vitamin D-related interventions on multiple sclerosis relapses: a meta-analysis.
http://www.ncbi.nlm.nih.gov/pubmed/23698130
„We found no significant association between high-dose vitamin D treatment and risk of MS relapse. In conclusion, although no
significant association between high-dose vitamin D treatment and risk of MS relapses was found, the studies were limited by
several methodological limitations. Further larger, more prolonged studies are merited.“
30. 5. 2013; PubMed.gov; Comparison of Vitamin D3 Serum Levels in New Diagnosed Patients with Multiple Sclerosis
versus Their Healthy Relatives.
http://www.ncbi.nlm.nih.gov/pubmed/23737310
"Compared to the healthy subject, serum levels of vitamin D were significantly lower in patients with MS. This difference was only
significant in women. Observed difference of vitamin D levels of both groups were significant in summer. This study continues to
support the role of vitamin D deficiency in MS."
13. 6. 2013; PubMed.gov; Higher levels of reported sun exposure, and not vitamin D status, are associated with less
depressive symptoms and fatigue in multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/23763464
„CONCLUSION: We found that higher levels reported sun exposure, rather than 25(OH)D levels, were associated with less
depressive symptoms and levels of fatigue. The role of UV or light therapy will need to be evaluated in randomized controlled trials
to confirm an effect on these symptoms in MS.“
Mai 2013; PubMed.gov; Vitamin d3 concentration correlates with the severity of multiple sclerosis.
http://www.ncbi.nlm.nih.gov/pubmed/23930170
„CONCLUSIONS: Our findings not only further disclose the lower level of vitamin D in MS patients in comparison with healthy
controls, but also support the association between vitamin D and disease severity in MS.“
17. 9. 2013; Aktiv mit MS; Niedrige Vitamin-D-Spiegel erhöhen MS-Risiko
http://www.aktiv-mit-ms.de/ms-news/ms-ticker/detail/artikel/niedrige-vitamin-d-spiegel-erhoehen-ms-risiko/
2013; Iran J. of Neurology; Is serum vitamin D levels associated with disability in patients with newly diagnosed multiple
sclerosis?
http://www.ncbi.nlm.nih.gov/pubmed/24250900
„CONCLUSION: Our findings did not suggest a protective association for serum vitamin D levels against disability in MS patients.“
27. 11 2013; eifelzeitung.de; Pilze sind die Vitamin D-Lieferanten in der dunklen Jahreszeit
http://www.eifelzeitung.de/2013/11/pilze-sind-vitamin-d-lieferanten-in-dunklen-jahreszeit-47626/
Anm.: oder Olerovit D3 (Kostet in der Apotheke etwa 2 €) ...
10. 12. 2013; NetDoktot.de; Vitamin D: Wie das Sonnenvitamin Multiple Sklerose stoppt
http://www.netdoktor.de/News/Vitamin-D-Wie-das-Sonnenvit-1138101.html?utm_source=Newsletter+11.12.2013&utm_medium=E-
Mail&utm_term=Vitamin-D-Wie-das-Sonnenvitamin-Multiple-Sklerose-stoppt&utm_content=1
30. 9. 2013; PubMed.gov; [The impact of the vitamin D in neurological diseases and neurorehabilitation: from demencia to
multiple sclerosis. Part I: the role of the vitamin D in the prevetion and treatment of multiple sclerosis].
http://www.ncbi.nlm.nih.gov/pubmed/24358684
„There is no consensus for the role of vitamin D in multiple sclerosis yet, but until the achieving this, the diagnosis and the
treatment of the vitamin D deficiency is crucial for scelrosis multiplex patients and in cases of elevated risk. Data shows, that in
patient with multiple sclerosis the normal vitamin D level is suboptimal, however the exact role of vitamin D and doses must be
clarified by interventional studies.“
17. 9. 2013; Multiple Sclerosis Didcovery forum; Single Calcitriol Dose Beats Back EAE in Mice - Vitamin D zaps
inflammatory T cells in the CNS and leads to sustained remission
http://www.msdiscovery.org/news/new_findings/7593-single-calcitriol-dose-beats-back-eae-mice
„Just a single dose of calcitriol - he active form of vitamin D—reversed paralysis in mice with an experimental form of multiple
sclerosis, a new study finds. Once established, the relapse could be maintained through dietary supplementation with the vitamin.“
Anm.: Calcitrol ist ethalten in Rohaltrol
®
, wird gegeben beim sek. Hyperparathyreoidismus, ist indikationspflichtig, bedarf
regelmäßiger Kontrollen des Ca-Spiegels.
10. 1. 2014; DMSG; Kann Vitamin D die Multiple Sklerose bremsen?
http://www.dmsg.de/multiple-sklerose-news/index.php?w3pid=news&kategorie=forschung&anr=4957
17. 1. 2014; ÄrzteZeitung; Bei erstem MS-Schub - Wenig Vitamin D, schlechte Prognose
http://www.aerztezeitung.de/medizin/krankheiten/neuro-
psychiatrische_krankheiten/multiple_sklerose/default.aspx?sid=852803&cm_mmc=Newsletter-_-Newsletter-C-_-20140117-_-
Multiple+Sklerose
20. 1. 2014; PubMed.gov; Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression.
http://www.ncbi.nlm.nih.gov/pubmed/24445558
21. 1. 2014; aerzteblatt.de; Multiple Sklerose: Vitamin D könnte Krankheitsverlauf verlangsamen
http://www.aerzteblatt.de/nachrichten/57282
23. 1. 2014; pressetext.com; Vitamin D kann Multiple Sklerose abwehren - Studie sieht Substanz als wichtigen Risikofaktor
für Krankheitsverlauf
http://www.pressetext.com/news/20140123001
24. 1. 2014; aerzteblatt.de; Vitamin D-Supplemente: Meta-Analyse sieht keinen Zusatznutzen
http://www.aerzteblatt.de/nachrichten/57336
31. 1. 2014; pressetext.com; Nichts für Athleten: Vitamin D2 schadet Muskeln
http://www.pressetext.com/news/20140131003
Feb. 2014; PubMed.gov; Supplementation and therapeutic use of vitamin D in patients with multiple sclerosis: Consensus
of the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology.
http://www.ncbi.nlm.nih.gov/pubmed/24604370
„There is no scientific evidence up to the production of this consensus for the use of vitamin D as monotherapy for MS in clinical
practice.“
20. 3. 2014; Aktiv mit MS; Einfluss von Vitamin-D-Status auf MS
https://www.aktiv-mit-ms.de/ms-news/ms-ticker/detail/artikel/einfluss-von-vitamin-d-status-auf-ms/
Mar 2011; Eur J Immunol. ; 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit
experimental autoimmune encephalomyelitis.
http://www.ncbi.nlm.nih.gov/pubmed/21287548#
„These data support a model wherein 1,25-(OH)(2) D(3) acts directly on pathogenic CD4(+) T cells to inhibit EAE.“
17. 11. 2014; vurado.de; Niedrige Vitamin-D-Spiegel lassen die MS vermutlich rascher fortschreiten
http://www.curado.de/niedrige-vitamin-d-spiegel-29036/
25. 11. 2014; amsel.de; Vitamin D gegen Fatigue bei Multipler Sklerose ?
http://www.amsel.de/multiple-sklerose-news/medizin/Vitamin-D-gegen-Fatigue-bei-Multipler-Sklerose_5534
9. 12. 2014; NetDoktor.de; Vitamin-D-Mangel macht depressiv
http://www.netdoktor.de/news/vitamin-d-mangel-macht-depressiv/?utm_source=Newsletter+16.12.2014&utm_medium=E-
Mail&utm_term=Vitamin-D-Mangel-macht-depressiv&utm_content=1
31. 12. 2014; PubMed.gov; Interferon Beta and Vitamin D Synergize to Induce Immunoregulatory Receptors on Peripheral Blood
Monocytes of Multiple Sclerosis Patients.
http://www.ncbi.nlm.nih.gov/pubmed/25551576
13. 1. 2015; PubMed.gov; Increased Circulating Levels of Vitamin D Binding Protein in MS Patients.
http://www.ncbi.nlm.nih.gov/pubmed/25590278
19. 1. 2015; MSlife; Vitamin D als Schlüsselhormon bei Multipler Sklerose
http://www.ms-life.de/ms-service/ms-news/detail/article/vitamin-d-als-schluesselhormon-bei-multipler-sklerose/
16. 3. 2015; MSIF; Vitamin D and neural stem cells
http://www.msif.org/news/2015/03/16/vitamin-d-neural-stem-cells/
12. 5. 2015; PubMed.gov; Treatment with Vitamin D/MOG Association Suppresses Experimental Autoimmune Encephalomyelitis.
http://www.ncbi.nlm.nih.gov/pubmed/25965341
24. 8. 2015; PubMed.gov; Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study.
http://www.ncbi.nlm.nih.gov/pubmed/26305103
26. 8. 2015; DMSG; Kanadische Studie belegt: Genetischer Vitamin-D-Mangel erhöht das Multiple Sklerose-Risiko
http://www.dmsg.de/multiple-sklerose-news/index.php?w3pid=news&kategorie=forschung&anr=5700
26.8.2015; heilpraxisnet.de; Zusammenhang nachgewiesen: Erhöhtes MS-Risiko bei Vitamin-D-Mangel
http://www.heilpraxisnet.de/naturheilpraxis/zusammenhang-nachgewiesen-erhoehtes-ms-risiko-bei-vitamin-d-mangel-
2015082643856
27. 8. 2015; amsel.de; Vitamin D für Angehörige von Menschen mit Multipler Sklerose ?
http://www.amsel.de/multiple-sklerose-news/medizin/Vitamin-D-fuer-Angehoerige-von-Menschen-mit-Multipler-Sklerose_5988
27. 8. 2015; aerzteblatt.de; Multiple Sklerose: Vitamin D-Gene beeinflussen Krankheitsrisiko
http://www.aerzteblatt.de/nachrichten/63936
27. 8. 15; amsel.de; Vitamin D für Angehörige von Menschen mit Multipler Sklerose ?
http://www.amsel.de/multiple-sklerose-news/medizin/Vitamin-D-fuer-Angehoerige-von-Menschen-mit-Multipler-Sklerose_5988
29. 12. 2016; PubMed.gov; Metabolomics: A potential way to know the role of vitamin D on multiple sclerosis.
https://www.ncbi.nlm.nih.gov/pubmed/28063332
7. 12. 2017; NetDoktor; Vitamin D: Vorsicht, Überdosis!!
https://www.netdoktor.de/news/vitamin-d-vorsicht-ueberdosis/?utm_campaign=367f3e6041-
nl_2017_12_08_1905364&utm_medium=email&utm_source=NetDoktor&utm_term=0_039f3122ca-367f3e6041-205381437
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